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Index > Protein center > BID(Gene name) > Human
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  • BID (Gene name),
  • BH3-interacting domain death agonist (Protein name ),  BID_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Related Databases
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  • Gene name:
    BID;
    Protein name:
    BH3-interacting domain death agonist;
    Alternative:
    p22 BID(BID);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Forms heterodimers either with the pro-apoptotic protein BAX or the anti-apoptotic protein Bcl-2 (By similarity). p15 BID interacts with ITCH.
    Function:
    The major proteolytic product p15 BID allows the release of cytochrome c (By similarity). Isoform 1, isoform 2 and isoform 4 induce ICE-like proteases and apoptosis. Isoform 3 does not induce apoptosis. Counters the protective effect of Bcl-2.
    Subcellular Location:
    Isoform 2 Mitochondrion membrane A significant proportion of isoform 2 localizes to mitochondria, it may be cleaved constitutively.
    Protein Attributes:
    Sequence length:
    195
    Sequence:
    50:
    MDCEVNNGSS | LRDECITNLL | VFGFLQSCSD | NSFRRELDAL | GHELPVLAPQ | 
    100:
    WEGYDELQTD | GNRSSHSRLG | RIEADSESQE | DIIRNIARHL | AQVGDSMDRS | 
    150:
    IPPGLVNGLA | LQLRNTSRSE | EDRNRDLATA | LEQLLQAYPR | DMEKEKTMLV | 
    195:
    LALLLAKKVA | SHTPSLLRDV | FHTTVNFINQ | NLRTYVRSLA | RNGMD
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    SMR:
    UniGene:
    MIM:
    KEGG:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Human BH3-interacting domain death agonist
    Cat.:
    E0629h
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Human BH3-interacting domain death agonist
    Cat.:
    E0629r
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    MSDS:
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    96T
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    ELISA Kit for Human BH3-interacting domain death agonist
    Cat.:
    E0629m
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    MSDS:
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    96T
    ELISA Kit for Human BH3-interacting domain death agonist
    Cat.:
    E0629c
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Human BH3-interacting domain death agonist
    Cat.:
    E0629p
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    Packing:
    96T
    CLIA Kit for Human BH3-interacting domain death agonist
    Cat.:
    U0629c
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human BH3-interacting domain death agonist
    Cat.:
    U0629h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human BH3-interacting domain death agonist
    Cat.:
    U0629r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human BH3-interacting domain death agonist
    Cat.:
    U0629m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human BH3-interacting domain death agonist
    Cat.:
    U0629p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human BH3-interacting domain death agonist
    Polyclonal Antibody for Human BH3-interacting domain death agonist
    Cat.:
    P0629Rb-m
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human BH3-interacting domain death agonist
    Cat.:
    P0629Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human BH3-interacting domain death agonist
    Polyclonal Antibody for Human BH3-interacting domain death agonist
    Cat.:
    P0629Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human BH3-interacting domain death agonist
    Monoclonal Antibody for Human BH3-interacting domain death agonist
    Monoclonal Antibody for Human BH3-interacting domain death agonist
    Monoclonal Antibody for Human BH3-interacting domain death agonist
    Monoclonal Antibody for Human BH3-interacting domain death agonist
    Protein for Human BH3-interacting domain death agonist
    Protein for Human BH3-interacting domain death agonist
    Protein for Human BH3-interacting domain death agonist
    Protein for Human BH3-interacting domain death agonist
    Protein for Human BH3-interacting domain death agonist

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE (ISOFORM 1)
    2. 2.
      "The gene for death agonist BID maps to the region of human 22q11.2 duplicated in cat eye syndrome chromosomes and to mouse chromosome 6."
      Footz T.K. , Birren B. , Minoshima S. , Asakawa S. , Shimizu N. , Riazi M.A. , McDermid H.E.
      Genomics51:472-475(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
    3. 3.
      "Three novel Bid proteins generated by alternative splicing of the human Bid gene."
      Renshaw S.A. , Dempsey C.E. , Barnes F.A. , Bagstaff S.M. , Dower S.K. , Bingle C.D. , Whyte M.K.
      J. Biol. Chem.279:2846-2855(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1; 2; 3 AND 4);SUBCELLULAR LOCATION;TISSUE SPECIFICITY;FUNCTION
    4. 4.
      "Cloning and expression of a new human cDNA homology to murine apoptic death agonist (BID) mRNA."
      Dai F.Y. , Yu L. , Huang H.B. , Jiang C.L. , Cui Y.Y. , Zhao S.Y.
      Submitted (2003-07) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
    5. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
    6. 6.
      "Cloning of human full open reading frames in Gateway(TM) system entry vector (pDONR201)."
      Ebert L. , Schick M. , Neubert P. , Schatten R. , Henze S. , Korn B.
      Submitted (2004-05) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
    7. 7.
      NIEHS SNPs program
      Submitted (2003-05) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANT GLY-10
    8. 8.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2);VARIANT GLN-162
      tissue: Brain.
      tissue: Skin.
    9. 9.
      "Immunoaffinity profiling of tyrosine phosphorylation in cancer cells."
      Rush J. , Moritz A. , Lee K.A. , Guo A. , Goss V.L. , Spek E.J. , Zhang H. , Zha X.-M. , Polakiewicz R.D. , Comb M.J.
      Nat. Biotechnol.23:94-101(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-54;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    10. 10.
      "ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage."
      Matsuoka S. , Ballif B.A. , Smogorzewska A. , McDonald E.R. III , Hurov K.E. , Luo J. , Bakalarski C.E. , Zhao Z. , Solimini N. , Lerenthal Y. , Shiloh Y. , Gygi S.P. , Elledge S.J.
      Science316:1160-1166(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-78;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Embryonic kidney.
    11. 11.
      "The ubiquitin ligase Itch mediates the antiapoptotic activity of epidermal growth factor by promoting the ubiquitylation and degradation of the truncated C-terminal portion of Bid."
      Azakir B.A. , Desrochers G. , Angers A.
      FEBS J.277:1319-1330(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH ITCH;UBIQUITINATION BY ITCH
    12. 12.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    13. 13.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT MET-1;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    14. 14.
      "Solution structure of BID, an intracellular amplifier of apoptotic signaling."
      Chou J.J. , Li H. , Salvesen G.S. , Yuan J. , Wagner G.
      Cell96:615-624(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR
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